- S Club 7
- S Club 8 (S Club Juniors)
- S.C.A.L.P.
- S.O.D. (Stormtroopers Of Death)
- S.T.U.N.
- Saafir
- Sacred Reich
- Sacred Rite
- Sacrilege
- Sadaharu
- Sade
- Safety in Numbers
- Saga
- Sage Francis
- Sahara Hotnights
- Saint Etienne
- Saint Vitus
- Salad
- Salem
- Saling Ket
- Saliva
- Salt N Pepa
- Sam Nicosia
- Sam Phillips
- Sam Roberts
- Samael
- Samantha Cole
- Samantha Fox
- Samantha Mumba
- Samiam
- Sammath
- Sammie
- Sammy Hagar
- Sammy Hagar & The Waboritas
- Sammy Kershaw
- Samson
- Sanatorium
- Sanctifica
- Sanctus Real
- Sandra
- Sandy Denny
- Santana
- Saosin
- Sara Evans
- Sara Groves
- Sarah Brightman
- Sarah Connor
- Sarah Fimm
- Sarah Harmer
- Sarah Hudson
- Sarah McLachlan
- Sarah Slean
- Sarai
- Saratoga
- Sarcofago
- Sargeist
- Sarina Paris
- Sash!
- Sasha
- Sasha Lazard
- Satanic Surfers
- Satariel
- Sathanas
- Satyricon
- Sauce Money
- Saukrates
- Savage Garden
- Savatage
- Save Ferris
- Saves the Day
- Saving Jane
- Saviour Machine
- Savoy Brown
- Sawyer Brown
- Saxon
- Say Anything
- Saybia
- Scallywagon
- Scandal'Us
- Scanner
- Scar Culture
- Scarface
- Scarling
- Scars Of Life
- Scars Of Tomorrow
- Scarve
- Scary Kids Scaring Kids
- Scatter The Ashes
- Scatterbrain
- Scattered Fall
